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  • Zylkene Plus Calming Supplement for Large Dogs 15 to 60kg - 30 Capsules

Zylkene Plus Calming Supplement for Large Dogs 15 to 60kg - 30 Capsules By Zylkene

30Reviews
Price per Pack

RRP £63.13

2 PacksBottomless Bowl£56.39Free Delivery-11%
2 PacksOne Time Purchase£56.39Free Delivery-11%
1 PackBottomless Bowl£57.40-9%
1 PackOne Time Purchase£57.40-9%

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Zylkene Plus 450mg is a complementary feeding supplement designed to support emotional well-being in large dogs weighing 15–60kg, helping them cope with prolonged or recurring challenging situations. This advanced dual-ingredient formula supports calm behaviour without causing drowsiness and is suitable for long-term use. Capsules can be opened and sprinkled onto food for easy daily administration.
  • Supports emotional balance in dogs during prolonged or recurring challenging situations
  • Dual-action formula combining a natural milk protein and white fish muscle hydrolysate
  • Helps support calm behaviour without sedation or drowsiness
  • Easy-to-give capsules that can be opened and mixed with food
  • UK’s No.1 veterinary calming supplement, widely used and trusted by vets
Powder (450mg): Casein (trypsin hydrolysed bovine casein) 47.6%, maltodextrin, fish proteins hydrolysed 19.0%, magnesium stearate.
Crude Protein 54%, Crude Fat 1.5%, Crude Ash 10%, Moisture 6.0%, Crude Fibre 5.5%.
For oral administration. Give the full daily amount in one intake. Capsules can be opened and mixed with food.

Longer term use: Administer daily for 1 month, then reassess your dog’s behaviour and continue if needed.

Daily Amount:
15–30kg body weight: 1 capsule per day
30–60kg body weight: 2 capsules per day

Zylkene Plus is a complementary feeding stuff for dogs and cats and not a veterinary medicine.
Store at room temperature. Keep tightly closed after opening and use within 90 days. Keep out of sight and reach of children.

Ratings & Reviews

30 reviews

  • 3 stars
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  • 1 star
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9/8/2025 3:40:00 PM

Highly pleased

by Rose Turner -

Great for reducing his general background worry and making him more receptive to training I highly recommend them

21/6/2025 5:03:00 PM

Reliable calm

by Stanley Ward -

This product consistently provides a gentle calming effect without making my active dog drowsy

31/8/2025 7:14:00 PM

Easy transition

by Quentin Smith -

Helped my new large rescue dog settle into the chaos of a busy family home He seems much more confident now

12/7/2025 4:14:00 PM

Good for recovery

by Patricia Reed -

Used this after surgery to keep my dog calm and settled during his rest period It worked wonderfully

11/9/2025 5:29:00 PM

Only a mild effect

by Oscar Quinn -

My Saint Bernard is still quite anxious around strangers despite using these for a few weeks Maybe they are better for noise fears

12/5/2025 8:59:00 AM

Worth the investment

by Natalie Price -

I was skeptical but the calming effect is real and it has improved my dog's quality of life immensely

5/8/2025 3:46:00 PM

Perfect dosage

by Miles Owens -

The strength is just right for a large breed dog I sprinkle it on her breakfast and she eats it right up

28/7/2025 8:25:00 AM

Recommended by trainer

by Laura Nelson -

My behaviorist suggested this plus formula and it's been a useful tool in his training program for reactivity

2/6/2025 10:43:00 AM

Brilliant for separation

by Joanna Lane -

My large dog's destructive behavior when left alone has reduced significantly since starting these capsules

8/10/2025 8:13:00 PM

Really takes the edge off

by Kenneth Marsh -

Great for my large Shepherd who gets overexcited and anxious at new environments Helps her settle down quickly

28/9/2025 11:34:00 AM

Great value pack

by Ian King -

Good amount of capsules for a month's supply and the effect is clearly positive for my medium sized pup

26/9/2025 10:05:00 AM

Highly satisfactory

by Holly Jarvis -

My dog is happier and less stressed and that makes me happy too Great natural product

1/7/2025 10:51:00 AM

Easy to hide

by Gareth Hunt -

I just slip the capsule into a piece of cheese and he takes it without noticing Very convenient

3/9/2025 10:43:00 AM

Settles well at night

by Eileen Finch -

He used to wake up frequently but is now sleeping through the night consistently since taking this supplement

19/5/2025 8:49:00 PM

Good product

by Dennis Eyre -

Helped my anxious Beagle a little but it didn't completely solve the problem Maybe a slightly better effect than the regular Zylkene

20/5/2025 8:32:00 AM

Works on big events

by Chloe Drew -

We use them primarily for fireworks and car travel and they definitely make him more relaxed and manageable

2/5/2025 8:33:00 AM

Very effective

by Zoe Allen -

My rescue mutt used to have severe separation anxiety but these capsules have helped manage it alongside training

1/5/2025 9:20:00 PM

Best calming aid

by Barry Cole -

Tried a few different supplements but this plus version for medium dogs is by far the most successful for my lab mix

24/10/2025 4:11:00 PM

Noticeable improvement

by Yannick Young -

Saw a positive change in my spaniel's general nervousness around people and noise after two weeks

20/5/2025 11:19:00 AM

Excellent for reactivity

by Wilma Xander -

My border collie is much less reactive on walks when she has these capsules daily Highly recommend the plus formula

20/9/2025 10:12:00 AM

Happy with purchase

by Victor Walsh -

My small dog used to whine constantly when left alone This has lessened significantly since starting these capsules

13/5/2025 12:34:00 PM

Reliable supplement

by Teresa Vance -

I trust this brand and the plus formula seems to be more effective than the regular one for my highly anxious dog

24/10/2025 8:48:00 PM

Worth the cost

by Scott Underwood -

This product is a little expensive but the benefits for my pet's happiness make it completely worth the investment

22/10/2025 9:28:00 PM

Positive results

by Rita Thompson -

Used it for a feral rescue cat and it's helped her settle into indoor life She is much less jumpy

9/9/2025 3:47:00 PM

Only slight improvement

by Quentin Shaw -

I think it helped marginally but my cat's behavioral issues are complex Might need to try a different approach