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Zylkene Calming Supplement for Dogs 15-60kg - 20 capsules By Zylkene

10Reviews
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RRP £37.24

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Zylkene 450mg is a calming supplement for large dogs weighing 15–60kg, designed to help them cope with short-term challenging situations such as loud noises, social gatherings, travelling, vet visits or changes in routine. Containing a natural milk protein with clinically proven calming effects, it helps support relaxed behaviour without causing drowsiness and is easy to administer by opening the capsule and sprinkling the powder onto food.
  • Helps dogs cope with short-term challenging or stressful situations
  • Contains a natural milk protein with clinically proven calming effects
  • Supports emotional balance without causing drowsiness
  • Easy-to-administer capsules that can be opened and mixed with food
  • UK’s No.1 veterinary calming supplement, widely used and trusted by vets
Powder: Casein (trypsin hydrolysed bovine casein), magnesium stearate. Capsule: Bovine skin gelatine.
Powder: Casein (trypsin hydrolysed bovine casein) 82.9%, magnesium stearate.
Capsule: Bovine skin gelatine 17.1%.
Short-term use: Begin 1–2 days before the expected stressful event.

Longer-term use: Give daily for 1 month, then reassess behaviour and continue if needed.

Daily Amount:
15–30kg body weight: 1 capsule per day
30–60kg body weight: 2 capsules per day

The capsule can be opened and mixed with food. Always ensure clean, fresh water is available.
Store in a cool, dry place.

Ratings & Reviews

10 reviews

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12/7/2025 6:08:00 AM

Five stars

by Thomas King -

Fantastic natural calming aid for large dogs. It has made a huge difference to my dog's quality of life. Highly recommend

29/9/2025 4:48:00 PM

Took time to notice

by Maria Wilson -

It required consistent use for a couple of weeks before the calming effect was obvious. Don't expect instant results

10/6/2025 5:31:00 PM

Highly effective

by Daniel Robinson -

My large dog is much happier and calmer since I started him on this supplement. It's a great long term aid

5/7/2025 6:26:00 PM

Pricey but worth it

by Emily Carter -

The cost is high but I can't put a price on my dog's comfort. This product genuinely works to reduce his anxiety

14/6/2025 7:52:00 AM

Helps with vet visits

by James Brown -

My giant dog is terrified of the vet but these capsules make him much more manageable and less stressed for his checkups

21/8/2025 10:27:00 PM

Very reliable

by Sarah Miller -

The correct dosage for my large breed and it works consistently. I mix it into his food and he eats it without noticing

18/6/2025 4:19:00 PM

Great calming aid

by Peter Hall -

I use this for my large dog when we have builders or noise near the house. It really helps to keep him settled. Good value

7/5/2025 10:11:00 PM

Good for reactivity

by Laura Evans -

My dog is less reactive to other dogs on walks since starting these capsules. They help him think before he reacts

12/5/2025 10:38:00 AM

Effective and natural

by Daniel Taylor -

I love that this is a natural way to help with my large dog's general anxiety. He is much more relaxed in the evenings now

25/5/2025 11:12:00 AM

Essential for my large dog

by Chloe Adams -

My Labrador gets very anxious when left alone and this large dog formula has made a huge difference to her stress levels